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Studies should start with a low dose of 0.25mg, which should be increased gradually every four weeks to a maintenance dose of 2.4mg, based on the subject's tolerance [32]

The mixture is then filtered through sterilizing filters (0.22 m) and filled into sterile vials in an aseptic environment

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However, the dynamic BBB model has a lot of shortcomings: it is not possible to visualize the endothelial cells

Peripheral inflammation increases seizure susceptibility via the induction of neuroinflammation and oxidative stress in the hippocampus