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Unanticipated reactions can skew results, invalidate months of work, and lead to incorrect conclusions
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Back Black, J (8 dec 1988) 'Nobel Lecture: Drugs from emasculated hormones: the principles of syntopic antagonism'
[33] In Ancient Greece, the physician Hippocrates (460370 BC) described symptoms of scurvy, specifically a "swelling and obstruction of the spleen." [34] [35] Pliny the Elder described sailors consuming sea kale to prevent scurvy in his Naturalis historia (7779 AD)
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