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Therefore, future research must prioritize improvements in longitudinal studies to address differences between rodent and human autoimmunity progression during the asymptomatic first and second phases of T1D pathogenesis

Once reconstituted with bacteriostatic water, refrigeration is essential and the solution should be used within 2 to 4 weeks

47,48 Moreover, active or inactive drug metabolites can influence both efficacy and adverse effects, as seen with prodrugs such as cyclophosphamide

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