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Theoretical concerns exist for individuals with active cancer due to angiogenic properties, though research hasn't identified increased cancer risk
B-100 complex can interfere with other medicines including but not limited to: levodopa, medicines containing oestrogen, hydrazine, certain anti epileptic drugs, phenobaritone, phenytoin, immunosuppressants and some drugs used to treat infections such as isoniazid, pyrazinamide, cycloserne and penicillamine
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Each time, vary the injection site (alternate legs, for instance) to prevent soreness or muscle irritation
Informal protocols generally avoid doubling the next amount because safety and dose limits are unknown
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