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It is considered to belong to the Class B family of GPCRs whose members possess an extracellular N-terminal domain of 100-150 amino acids connected to the 7TM domain core typical of all G protein receptors (26)
doi: 10.1056/NEJMoa2501006 91 ParabPChaudharyPMukhtarSMoradiAKodaliAOkoyeCet al
Originally designed to treat type 2 diabetes, it found a second, unexpected life as one of the most effective weight-loss drugs ever developed
A multi-receptor peptide studied for activity across GLP-1, GIP, and glucagon pathways, used in metabolic and endocrine signaling research
CXO Perspective 3.3
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