Integrating network pharmacology and bioinformatics to explore the effects of dangshen (codonopsis pilosula) against hepatocellular carcinoma: validation based on the active compound luteolin
There were faster granulation tissue formation, re-epithelialization, dermal remodeling, and collagen deposition through extracellular signalregulated kinases (ERK)1/2 signaling pathway as well as its downstream targets, including c-Fos, c-Jun, and egr-1
10.1080/10715762.2021.1873318 16 GuoY.WenJ.HeA.QuC.PengY.LuoS.et al (2023)
In the high-dose treatment group, they reported statistically significant improvements in the total score, the motor subscore, and the non-motor subscore
however, translating it into the real world for skin lightning is complex