However, metformin extended-release preparations are absorbed into the bloodstream through intestinal transit proteins in about 50% of the amount of the regular preparations, but they have similar glucose-lowering effects compared to the regular preparations (Buse et al., 2016)
Randomized controlled trials before the issue of CVOTs by the FDA in 2008 mainly focused on the efficacy of the blood glucose-lowering effects and a broad spectrum of adverse effects, with limited numbers of cardiovascular adverse events and relatively short follow-up duration
Many chronic sinus issues are rooted in: Mold and mycotoxin exposure Food sensitivities (especially dairy and gluten) Gut dysbiosis Leaky gut Histamine intolerance or MCAS Immune system overload You dont fix that with a nasal spray
Carnitine deficiency impairs the mitochondrial -oxidation of FAs, leading to acute metabolic decompensation, elevated aminotransferase, and hepatic encephalopathy similar to NAFLD (75)
This is also a good time for your first body composition assessment (DEXA scan or equivalent)