This is most relevant in patients with pernicious anaemia receiving initial replacement therapy and requires monitoring of electrolytes
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In addition, decreased expression of genes related to DNA replication and repair, notably HBL79_RS03605 and HBL79_RS03835 , was observed, indicating that the efficiency of DNA replication and repair mechanisms was reduced (Figure 4I)
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In brief, the SURPASS-2 trial randomly assigned individuals with type 2 diabetes in a 1:1:1:1 ratio, to receive tirzepatide at a dose of 5 mg, 10 mg or 15 mg or semaglutide at a dose of 1 mg