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Furthermore, GLP-1 receptor agonists demonstrate pleiotropic effects, including significant improvements in glycemic control and lipid metabolism parameters 8,9

For now, it is best to think of retatrutide as an example of where medical weight loss is headed, with more data still needed to fully understand long-term outcomes and safety

As of now, there are no published clinical trials or studies in the UK validating its safety, efficacy, or long-term results

Notably, higher levels of infiltration of fat into muscles are associated with decreased muscle strength and deficits in function

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