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They expect to see a dramatic shift, but the body is still just laying the groundwork
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The pathophysiologic rationale is robust, targeting the neurogenic inflammation and central sensitization propagated by the trigeminovascular system, and the preliminary clinical data demonstrate safety and efficacy
The study did not address long-term safety, as most trials had a follow-up duration of one year or less
Xu, Association of semaglutide with risk of suicidal ideation in a real-world cohort
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