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3000 10 : 6,050,000 .5,700,000 : 5,700,000

For example, lower levels may be a factor in many health problems that are more common in older people

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The ARC, a key site of the hypothalamus, receives direct signals from the periphery, and it contains both orexigenic neurons expressing Agouti-related peptide (AgRP)/NPY and anorexigenic neurons expressing POMC (27)