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Eryptosis: Programmed death of nucleus-free, iron-filled blood cells

two published tirzepatide case series (Naranjo "probable"), FAERS reporting odds ratio 22.55 for allodynia across GLP-1 with tirzepatides neuro-AE proportion lower than semaglutides, class cohort signal (aHR 2.15) in related agents

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Deletion of RIP3 induced a shift from necroptosis to apoptosis in a HFD-mouse model, correlating with increased inflammation and hepatocyte apoptosis, as well as an early fibrotic response

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