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Its likely that GLP-1 RAs (or their combinations) will be part of a future MASH therapy regimen, given weight loss is the cornerstone treatment and GLP-1 causes weight loss plus some direct hepatic fat reduction
Maximal effects typically occur at four to six weeks, with full tissue remodeling continuing over three to six months
Low likelihood of approval: If you dont have type 2 diabetes, getting approved is extremely difficulteven if your doctor recommends it for medical reasons related to weight
Cynthia Thurlow: [00:43:56] What for you are some of the high-level reasons why women are dealing with unique challenges at this stage of life in terms of why do they suddenly become weight loss resistant, why do they start-- If they maybe weren't struggling in their 20s and 30s, they start to struggle quite a bit with this metabolic health issue
It is also used to lower blood sugar levels and decrease the risk of serious cardiovascular events such as stroke or heart attack in type 2 diabetes patients
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