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Lastly, insurance coverage and cost can also be determining factors, as some plans may favor one medication over the other
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*Recudes Oidative Stress
Metformin, if not contraindicated, is the preferred first line pharmacological agent for type 2 diabetes 14
Thus, it seems logical that stressed erythrocytes should be cleared from circulation before hemolysis occurs to avert proinflammatory and highly detrimental lytic destruction
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