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If your pen has been left out at high temperatures, it is no longer safe to use
Rare but serious effects exist, including pancreatitis, gallbladder problems, kidney injury from dehydration, and serious allergic reactions
However, rapid or substantial weight loss from any causewhether medication, dietary changes, or illnesscan result in loss of both adipose (fat) tissue and lean muscle mass
Diabetes Obes Metab 20:113120
However, more clinical trials will need to be included to overcome the limited sample size and complement these findings.
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