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While the absolute risk appears very low, NAIONs potential for irreversible vision loss justifies careful monitoring and informed counselling

These factors can shape not only which medications are prescribed, but also whether patients remain on therapy or transition to alternatives

Compared with all other drugs, tirzepatide was associated with a higher likelihood for multiple gastrointestinal adverse events, pancreatitis, biliary colic, diabetic retinopathy and medullary thyroid cancer

Thyroid disease: assessment and management (NG145)

Clinical trials have demonstrated that Trulicity effectively reduces HbA1c (a measure of average blood glucose over the preceding two to three months) and may also contribute to modest weight loss in some patients