This modest requirement is easily met through regular consumption of animal products: a single portion of salmon provides approximately 3 micrograms, whilst 100g of beef supplies around 2 micrograms
This mechanism also explains why some users feel cold during treatment while others actually feel warmer
If youre traveling, use an insulated cooler or a medication travel case to keep it at the right temperature
Other Causes of Reduced Pseudocholinesterase Activity Disease states Drugs (e.g., organophosphates, neostigmine , pyridostigmine) Effects: Prolonged paralysis , including diaphragm involvement Risk of respiratory failure Dibucaine Test Used to diagnose enzyme deficiency: Normal: ~80% inhibition Heterozygotes: 5060% Homozygotes: 2030% Management: Maintain sedation and mechanical ventilation Monitor recovery using train-of-four stimulation Other Contraindications History of malignant hyperthermia Conditions predisposing to overexpression of nAChRs, resulting in an increased incidence of life-threatening hyperkalemia, ventricular arrhythmias and acute rhabdomyolysis (Cooperman 1970
Monitoring for dehydration is essential, particularly during the first several weeks of treatment or after dose increases