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Across multiple late-breaking ADA presentations, investigators delivered pivotal data on once-monthly injectables, oral GLP-1 agonists, and novel co-agonist therapies, reporting clinically meaningful weight loss, improved glycemic outcomes, and good tolerability- safety profile in both people leaving with overweight or obesity with and without type 2 diabetes (T2D)

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Moreover, the remaining two studies [27, 29] did not specify a duration of the disease for inclusion, and the time since diagnosis in these studies was much higher than in McGarry [30] and Meissner [31], as shown in Table 3 [27, 29]

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