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Their physical structure changes how your body absorbs them: Orforglipron is a synthetic small-molecule compound
That said, clinical practice has established general switching guidelines
[12] Tirzepatide is also available in the UK in two licensed forms: Mounjaro is licensed for the treatment of type 2 diabetes, whilst Zepbound has received MHRA approval specifically for chronic weight management in adults
Synthetic GLP-1 drugs can be effective but may carry long-term risks
Journal of Alternative Complementary Medicine
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