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These are associations rather than proof that altering NNMT activity reverses metabolic changes, but they motivate continued research into NNMT inhibitors in metabolic models

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Cordova, J

5-Amino-1MQ functions as a small-molecule inhibitor of NNMT, the enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide

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