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PMID: 25415472 Bajramagic S, Sever M, Rasic F, et al

Constipation Slower gastric motility means slower bowel transit

These neurons may be associated with anorexigenic POMC neurons and/or orexigenic AgRP neurons (24), or they may be associated with the brain, such as non-POMC anorexigenic neurons in the ARN, which have glutamatergic connections with the paraventricular nucleus of the hypothalamus (45)