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In addition, a 2024 study found that people taking another GLP-1 drug, liraglutide, had a 179% higher risk of developing NAION
[64], which involved a co-culture of primary astrocytes with the bEnd.3 endothelial cell line, incubation with exendin-4 reduced the levels of the astrocyte-derived vascular endothelial growth factor (VEGF-A), matrix metalloproteinase-9 (MMP-9), chemokine monocyte chemoattractant protein-1 (MCP-1), and the chemokine C-X-C motif ligand 1 (CXCL-1), induced by oxygenglucose deprivation (OGD), and subsequently led to the increased expression of tight junction proteins in the bEnd.3 cells
This review aims to function as a comprehensive reference for clinical and laboratory findings for clinicians who are confronted with pediatric and adult patients with a possible diagnosis of a lcFAOD
Both compounded and brand-name GLP-1 formulations can produce injection site reactions, but the reaction profiles may differ because the supporting ingredients differ
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