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The evidence is pharmacokinetic and practice-based, not controlled outcome evidence
Reported side effects are usually mild and short-lived
What they did: A two-phase study, first in a dish with human endothelial cells (HUVECs), then in a live rat with an ischemic limb (= they closed off the artery so that no blood reached the leg)
Presented for research literature review only Kutlik MT et al
This 10 mg/mL concentration has become the default for a reason
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