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The glutathione S-transferases: an update [PMID: 2646197] Laboratory literature summary: The glutathione S-transferases: an update

49,51,52 In addition, imbalanced glutamate and GABA activity may contribute to a link between depression and chronic pain

In the pivotal SURMOUNT-1 trial, participants without diabetes who took tirzepatide for 72 weeks lost an average of 16% of body weight at the 5 mg dose, 21.4% at the 10 mg dose, and 22.5% at the 15 mg dose, compared to just 2.4% in the placebo group