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Crucially, this study shifted the scientific paradigm from a simple model of "glutathione depletion" to a model of an "overwhelmed compensatory mechanism." The discovery that circulating immune cells in these patients actually have elevated glutathione levelswhile simultaneously suffering from a severe depletion of other protective enzymes like SOD2revealed that the cells are desperately, and unsuccessfully, trying to fight off a catastrophic level of oxidative damage
Researchers suggest that VIP may affect dendritic cells (DCs)
10.1667/RR3339.1 44 MaiorinoM.UrsiniF
Faster results may be seen with medical supervision or injectable forms
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