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10.1016/j.vph.2018.02.010 76 VukojevicJ.VrdoljakB.MalekinusicD.SiroglavicM.MilavicM.KolencD.et al (2020)
the compound's evidence base is limited to preclinical in vitro and animal (largely rodent) studies of IGF-1 receptor activation, muscle-cell signaling, and tissue repair, with human safety and efficacy data for this specific analog effectively absent
In both studies, the mode of supplementation was via injection, which tends to involve high doses of vitamin B12, although precise dosages were not specified
It has been more than 28 days since reconstitution with bacteriostatic water, or more than 24 hours with sterile water
These medications are effective early in their use, but lose efficacy due to the formation of systemic antibodies against them over time
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