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P720R USP8 mutation is associated with a better responsiveness to pasireotide in ACTH-secreting PitNETs

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Additional studies demonstrated that SREBP-1c -/- mice had impaired induction of hepatic genes coding for fatty acid biosynthesis (e.g., acetyl-CoA carboxylase, fatty acid synthase, and stearoyl-CoA desaturase) compared to wild type mice [17]