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While the body does produce natural GLP-1, this endogenous hormone is rapidly broken down by the enzyme dipeptidyl peptidase-4 (DPP-4) within minutes of secretion, making it unsuitable as a therapeutic agent without pharmaceutical modification
Kwon R, Chang Y, Kim Y, et al
P., Preisendanz, S., Juma, S., Imrhan, V., Prasad, C., & Vijayagopal, P
In the efficacy estimand, mean change in body weight at 13 weeks was 5.5% with 60 mg NA-931, 8.7% with the 90 mg dose, 11.3% with 120 mg NA-931, and 13.8% with the 150 mg dose, compared with a 1.9% weight change for placebo
Diabetes care may involve other medications, additional lab monitoring, and clearance from your endocrinologist before you can proceed
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