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Inductively coupled plasma mass spectrometer (Agilent technologies 7700 series, USA) was used for quantitative analysis of the total ruthenium contents from different samples and cells
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10.2174/1570159X22666231103085859 Summary Keywords deuterium, copper, histidine, amyloidogenic proteins, cardiolipin, mitochondrial dysfunction, neurodegeneration Citation Seneff S and Kyriakopoulos AM (2025) Deuterium trafficking, mitochondrial dysfunction, copper homeostasis, and neurodegenerative disease
3 Mammalian CHAC2: defining its role in glutathione homeostasis, cancer progression and stem cell fate In addition to CHAC1, which is found exclusively in higher eukaryotes, organisms from bacteria to mammals possess a CHAC2 enzyme that exhibits a highly similar glutathione-specific GCT activity (Kaur et al., 2017)
This dose-tolerability relationship provides useful guidance for clinical protocol development
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