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in vivo male flinders sensitive line (fsl) rats and male cd1 mice, exposed to model genetic and environmentally induced depression, respectively, were injected intraperitoneally with alcar 100 mg/kg for 21 days

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Increase to 0.75mg (0.15mL) for three additional trials before moving to 1.0mg (0.2mL)

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A lower heart rate during the initial stages of exercise may indicate a more efficient cardiovascular response, potentially allowing the athlete to perform at higher intensities before reaching a maximal heart rate