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The compound received FDA GRAS status for safety but was never approved as a drug because efficacy was insufficient for pharmaceutical registration
Vitamin B12 is a water-soluble nutrient essential for red blood cell production, DNA synthesis, and energy metabolism
5-Amino-1MQ competitively inhibits nicotinamide N-methyltransferase (NNMT) at its catalytic site
"Environmental-friendly catalysts learned from Vitamin B 12 -dependent enzymes" (PDF)
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