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It is about restoring your bodys ability to use fat as fuel and preserve lean mass
Complex roles of nicotinamide N-methyltransferase in cancer progression
Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent
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A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders
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