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Even small increases (2.5 to 5 pounds on an exercise, or one additional rep) count
Whether that difference is clinically meaningful depends entirely on what your goals are and what you've already achieved
Two are still open: TRIUMPH-7 (NCT07035093), for obesity or overweight with chronic low back pain, and the Phase 3 multi-agent MASLD master protocol (NCT07165028), which studies several drugs rather than retatrutide alone
Mislabeling, contamination and dosing error have all been reported
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