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Inagaki N, Takeuchi M, Oura T, et al

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Therefore, they are nowadays recommended as first line therapy in patients with T2DM and atherosclerotic cardiovascular disease to reduce events, regardless of baseline or target HbA1c and concomitant glucose-lowering medication according to the 2023 ESC guidelines for the management of cardiovascular disease in patients with diabetes [31]

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This strategy, known as multimodal analgesia, allows you to target pain through both the central and peripheral nervous systems simultaneously for superior relief