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Acknowledgements We are grateful to Jens Brning for providing the IR flox/flox mice
A deficiency can occur for several reasons, such as pernicious anemia (a condition where the body cannot absorb vitamin B12 from the diet), certain medical conditions (e.g., Crohn's disease, celiac disease), surgical removal of part of the stomach or intestine, or strict vegetarian/vegan diets if not adequately supplemented
It was initially added to GLP-1 to reduce adverse reactions to the medicine when administered
The PlexusDx Precision Peptide Genetic Test examines variants in genes including GIPR rs1800437, MC4R rs17782313, and FTO rs9939609each influencing how your body responds to GLP-1 compounds
Ann Emerg Med 2002, 39: 616-621
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