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However, its use is restricted to certified opioid treatment programs (OTPs), and it carries a risk of misuse, requiring close supervision

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PubMed Lau, D.C.W., Erichsen, L., Francisco, A.M., Satylganova, A., le Roux, C.W., McGowan, B., Pedersen, S.D., Pietilinen, K.H., Rubino, D., & Batterham, R.L

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Clinical research established that the most commonly effective range is 250-500 mcg (0.25-0.5 mg) administered once daily via subcutaneous injection