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Description

In some cases, Claimable submits appeals to both internal and external review simultaneously to compress the timeline

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the coupling in step 2 of the preparation method is performed by condensing with DIC+A or B+A+C until the resin is detected to be transparent with ninhydrin, wherein A is chosen from HOBt or HOAt, B is chosen from HBTU, HATU, TBTU, PyAOP, or PyBOP, C is chosen from DIPEA or TMP