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Treatment guidelines do not give a definite upper limit for basal insulin dose, and there may be the temptation to continue with a familiar routine by increasing the basal insulin dose despite the patient still not achieving glycemic targetsa situation known as over-basalization [10]

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Red meat and seafood are the primary sources of dietary creatine, while endogenous creatine is synthesized in the liver, kidneys, and pancreas

They also affect signals in the brain linked to feelings of fullness and satisfaction, tamping down appetite, food-related thoughts and cravings