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In SUSTAIN 6, subjects with T2D at high CV risk treated with semaglutide had a 26% lower risk of the primary composite outcome of first MACE (death from CV causes, nonfatal MI, or nonfatal stroke) vs those receiving placebo over 2 years (p = 0.02 for superiority [post hoc]) [12]
My doctor explained that illness can amplify existing side effects
Baseline co-morbidities The TRIUMPH-4 population had obesity plus knee osteoarthritis
Average body weight reduction over 68 weeks
The concentration changes proportionally
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