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Integrating the proteomic and metabolic datasets, we discovered that enzymes pivotal to cysteine biosynthesis, such as cystathionine beta-synthase (CBS) [27], and key glutathione biosynthesis genes, including glutamate-cysteine ligase catalytic subunit (GCLC) [28] and Glutamate-cysteine ligase regulatory subunit (GCLM) [29], were key downstream targets downregulated upon DDX3X inhibition (Fig
Siderophore uptake by Candida albicans: effect of serum treatment and comparison with Saccharomyces cerevisiae
The glucagon receptor component of retatrutide is responsible
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