In ALS, lower levels of GSH were found in the motor cortex and the corticospinal tractus in patients compared to healthy controls 12,13,14,15
doi: 10.3390/biom12050737 8 MagataFTsukamuraHMatsudaF
The most common side effects of GLP-1s are: Nausea Diarrhea Constipation Vomiting Abdominal pain Headache In most cases, these side effects improve as your body adjusts to the medication
Clin Exp Metastasis 15:32937, PMID: 9174132 Gmnder H, Roth S, Eck HP, Gallas H, Mihm S, Drge W (1990) Interleukin-2 mRNA expression, lymphokine production and DNA synthesis in glutathione-depleted T cells
Diana Mesa, RDN, LDN, CDCES, founder of En La Mesa Nutrition, agrees, adding that Berberine does have some similarities [to GLP-1 RA medications] in that it can trigger the pancreas to release insulin and helps make cells more sensitive to the effect of insulin, which is a characteristic similar to what Metformin [another prescription medication prescribed to treat type 2 diabetes and other off-label conditions] does. Still, she notes that its unclear whether or not Berberine has any appetite-suppressing effects like Ozempic and similar medications