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These changes are likely both direct effects of the medications themselves on the hypothalamus in the brain and ovaries, says Dr
KimWJeongMHChoSHYunJHChaeHJAhnYKet al
Not designed for rapid or significant weight reduction
The tirzepatide dosage protocol starts at 2.5 mg weekly with gradual increases, and Anthem typically wants to see this titration documented before approving ongoing coverage
Clinical Evidence: Blood Pressure Reductions in GLP-1 Trials The LEADER trial, which followed over 9,000 people taking liraglutide (a similar GLP-1 drug), documented average systolic blood pressure drops of 23 mmHg within the first weeks of treatment
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