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upregulates collagen I, III, elastin, and glycosaminoglycans
This aligns with anecdotal cases where individuals undergoing glutathione injections noticed their skin gradually becoming a shade lighter after about 1.52 months of treatment
Macrophages induce the expression of the neutrophil chemokine (C-X-C motif) ligand 8a (Cxcl8a) in cells under ERS, recruit neutrophils into islets thus promoting the loss of cells
Additionally, GSH shifts the melanogenesis pathway away from eumelanin (the darker brown/black pigment) toward pheomelanin (the lighter red/orange pigment) by interacting with dopaquinone intermediates in the Raper-Mason pathway
clinical use is not established
