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173 At the molecular level, gene modulation techniques, including siRNA- and shRNA-mediated silencing of efflux transporter genes (e.g., ABCB1, ABCG2), as well as CRISPR/Cas9-based gene editing, have successfully resensitized tumor cells to chemotherapy in preclinical models
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These previously unrecognized antidiabetogenic actions of GLP-1m may have therapeutic usefulness
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Very little drug is absorbed across the stomach wall
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