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LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a Phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial

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Tan says the 12 percent increase in gout risk reported in the study is a significant increase. Its possible GLP-1s could lead to temporary changes in uric acid level because of shifting fat-muscle ratios, she says