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CDK1 inhibition facilitates formation of syncytiotrophoblasts and expression of hCG [PMID: 29884303] Laboratory literature summary: CDK1 inhibition facilitates formation of syncytiotrophoblasts and expression of hCG

Neither option is objectively better

But weight loss-related amenorrhea is absolutely a thing

[25] Murine cells overexpressing the NADase CD38 consumed less oxygen, had higher lactate levels, and had abnormal mitochondria, including traits like missing or enlarged cristae, which lends more proof of NAD+s role in promoting mitochondrial and metabolic health

The logic follows: reduce inflammation, improve metabolism, lose weight