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6636, June 1997, pp
As hypothesized from the available structural data, the NH backbone of V12 serves as an oxyanion hole for the enolate formed upon deprotonation
In particular, while several studies suggest that -3 PUFA consumption has protective effects on the development of autoimmune thyroiditis [122], others demonstrate that exposure to pollutants (especially heavy metals) that contaminate fish is associated with an increased risk of autoimmunity and thyroid dysfunction [121,124,125,126]
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