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Alternatively, switching to a different GLP-1 medication may be considered if side effects are intolerable, as individual responses vary between agents

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Patients should contact their GP or prescribing clinician if they experience any of the following: Red flag symptoms requiring urgent assessment: Severe, persistent abdominal pain (possibly radiating to the back) with or without vomiting this could indicate acute pancreatitis, a known risk with GLP-1 receptor agonists as noted in the SmPC Right upper abdominal pain, fever, or yellowing of the skin/eyes potential signs of gallbladder disease, which is associated with Wegovy treatment and rapid weight loss Severe or worsening muscle/joint pain that is not relieved by simple analgesia Joint swelling, redness, or warmth suggesting possible inflammatory arthritis or infection Muscle weakness or difficulty with normal activities such as climbing stairs or lifting objects Signs of dehydration including dark urine, passing urine less often than normal, feeling dizzy, or extreme thirst particularly if unable to keep fluids down due to vomiting or diarrhoea Persistent fever accompanying muscle or joint pain For chest pain or severe breathlessness, call 999 immediately

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