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Research in rodent models of colitis demonstrated KPV reduced mucosal inflammation by 6070% compared to controls, and improved epithelial barrier function markers

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Mutat Res 702:123128 Ribas GS, Biancini GB, Mescka C et al (2012) Oxidative stress parameters in urine from patients with disorders of Propionate Metabolism: a beneficial effect of L-Carnitine supplementation

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The Effect of Nighttime Snacking on Cognitive Function in Older Adults: Evidence from Observational and Experimental Studies

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The framing is that adding a second agent adds a tolerability cost as well as a benefit, which is part of what a provider weighs before recommending both together

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