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Obesity is associated with several serious health conditions, including heart disease, stroke, and type 2 diabetes

Effectiveness can be more difficult to evaluate within that timeframe

While cardiovascular outcome data for retatrutide is still accumulating, the prudent approach for anyone with active cardiovascular disease is to remain on compounds with established cardiovascular safety profiles

Monitor for potential adverse effects including persistent gastrointestinal symptoms, signs of pancreatitis (severe abdominal pain radiating to the back), gallbladder disease (right upper quadrant pain, especially after meals), or changes in mood

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